Noninvasive diagnosis of portal hypertension using gadoxetate DCE-MRI of the liver and spleen

ConclusionsOur results demonstrate the potential utility of hepatocyte uptake parameters and spleen interstitial fraction obtained with gadoxetate DCE-MRI for the diagnosis of PH and CSPH.Key Points• Liver uptake and spleen interstitial fraction estimates from gadoxetate DCE-MRI are significantly correlated with portal pressure measurements.• Liver uptake rate shows good diagnostic performance for the diagnosis of portal hypertension.• The combination of liver uptake rate with spleen interstitial fraction exhibits excellent diagnostic performance for the diagnosis of clinically significant portal hypertension.

http://link.springer.com/10.1007/s00330-020-07495-0

Source: European Radiology - January 7, 2021 Category: Radiology Source Type: research