New research finds ginger counters certain autoimmune diseases in mice

(Michigan Medicine - University of Michigan) The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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CONCLUSION: This study shows that the thrombotic risk does not necessarily increase with the number of positive tests and raises the question of the therapeutic management of single aCL positive patients.PMID:34469630 | DOI:10.1111/jth.15518
Source: Thrombosis and Haemostasis - Category: Hematology Authors: Source Type: research
Ann Clin Lab Sci. 2021 Jul;51(4):552-556.ABSTRACTBACKGROUND: The antiphospholipid syndrome (APS) is an autoimmune disease that is characterized by thrombosis and/or pregnancy failure and associated with the presence of all or at least one of three standard antibodies (anti-phospholipid (aPL) antibodies, including lupus anticoagulant (LA), anti-cardiolipin (aCL), and anti-β2-glycoprotein I (anti-β2GPI)). A growing body of evidence recommends adding additional aPL antibodies, such as anti-phosphatidylserine (aPS), anti-prothrombin (aPT), and anti-annexin A5 (aAA5), to conventional laboratory tests (revised Sapporo ...
Source: Annals of Clinical and Laboratory Science - Category: Laboratory Medicine Authors: Source Type: research
We report here two cases of stroke associated with the presence of LA, and recall the strategy for screening for LA.PMID:34427558 | DOI:10.1684/abc.2021.1662
Source: Annales de Biologie Clinique - Category: Biochemistry Authors: Source Type: research
J Autoimmun. 2021 Jul 2;122:102689. doi: 10.1016/j.jaut.2021.102689. Online ahead of print.ABSTRACTElevated interleukin (IL)-21 is a common finding in the tissues and/or sera of patients with autoimmune disease. CD4 T cells are the primary producers of IL-21; often the IL-21 producing CD4 T cells will express molecules associated with follicular helper cells (TFH). Recent work has shown that the CD4 T cell-derived IL-21 is able to promote effector functions and memory differentiation of CD8 T cells in chronic infections and cancer. Autoimmunity has similarities to chronic infections and cancer. However, CD4 T cell-derived ...
Source: Journal of Autoimmunity - Category: Allergy & Immunology Authors: Source Type: research
More News: Antiphospholipid Syndrome | Autoimmune Disease | Biology | Ginger | Hughes Syndrome | Lupus