Surveillance of patients with conjunctival melanoma in German-speaking countries: A multinational survey of the German dermatologic cooperative oncology group

Conjunctival melanoma (CM) represents about 5% of all ocular melanomas with an incidence of 0.2 –0.8 per million [1]. It significantly differs from uveal melanoma (UM) and more closely resembles cutaneous melanoma. CM spreads via lymphogeneous and hematogeneous dissemination [2] and shows a clear UV light signature and high mutational burden [3]. BRAF, NRAS and KIT mutations are detected in up to 50%, 20% and 7%, respectively [2,4]. Primary tumours are mostly treated by local excision [5–7], often combined with adjuvant interventions [5,7,8].

Source: European Journal of Cancer - December 3, 2020 Category: Cancer & Oncology Authors: Anja Wessely, Theresa Steeb, Carola Berking, Max Schlaak, Markus V. Heppt, German Dermatologic Cooperative Oncology Group (DeCOG, committee ocular melanoma) Tags: Letter to the Editor Source Type: research