Regulation of XPA could play a role in inhibition of radiation-induced bystander effects in QU-DB cells at high doses
Conclusion: Gene expression profile was distinctive in bystander cells compared to target cells. The observed linear increasing of the ratio of XPA/BAX could support the hypothesis that the DNA repair system is stimulated and causes a reduction in RIBE at high doses.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Mohammad Taghi Bahreyni Toossi Hosein Azimian Shokouhozaman Soleymanifard Habibeh Vosoughi Elham Dolat Abdul Rahim Rezaei Sara Khademi Source Type: research