Effect of direct renin inhibition on vascular function after long-term treatment with aliskiren in hypertensive and diabetic patients

Conclusion: Aliskiren restored endothelial function and induced a more prompt peripheral vasodilation in hypertensive and diabetic patients possibly through the increased production of nitric oxide via the enhanced expression and function of the active phosphorylated form of endothelial nitric oxide synthase.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research