Management for lumbar spinal stenosis: Protocol for a network meta-analysis and systematic review.

Management for lumbar spinal stenosis: Protocol for a network meta-analysis and systematic review. J Orthop Surg (Hong Kong). 2020 Sep-Dec;28(3):2309499020975212 Authors: Wei FL, Liu Y, Zhou CP, Sun SG, Zhu KL, Du MR, Gao HR, Yuan YF, Song Y, Qian S, An B, Wang H, Li XX, Guo SK, Gao QY, Wu SD, Yan XD, Sun LL, Qian JX Abstract INTRODUCTION: Lumbar spinal stenosis (LSS) is caused by structural changes of the spine, which lead to several severe symptoms, including back pain, leg pain, numbness and tingling in the legs, as well as reduced physical function. However, there is little evidence suggesting whether a patient with LSS should be treated with surgery. If surgery is recommended, which type of surgery benefits the patient most? To answer these questions, we will conduct a network meta-analysis and a systematic review to compare surgical and nonsurgical interventions in terms of efficacy as well as safety in adult patients with LSS. METHODS AND ANALYSIS: We will search the PubMed, Cochrane library, and EMBASE databases for articles published prior to October 10, 2019. We will search for randomized controlled trials assessing surgical and nonsurgical interventions for adult patients with degenerative LSS without any language restrictions. The primary outcome measures will be pain and disability. The secondary outcomes will include adverse events (number of events or number of people with each type of adverse event), reoperati...
Source: Journal of Orthopaedic Surgery - Category: Orthopaedics Authors: Tags: J Orthop Surg (Hong Kong) Source Type: research