[Autophagy activation attenuates the neurotoxicity of local anaesthetics by decreasing caspase-3 activity in rats].

CONCLUSIONS: Enhancement of autophagy decreases caspase-3-dependent apoptosis and improves neuronal survival in vivo. Activation of autophagy may be a potential therapeutic strategy for local anaesthetic-induced neurotoxicity. PMID: 33280811 [PubMed - as supplied by publisher]
Source: Revista Brasileira de Anestesiologia - Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research