Postoperative radiotherapy for pathological stage IIIA ‐N2 non‐small cell lung cancer with positive surgical margins

ConclusionsFor pIIIA ‐N2 NSCLC patients with positive surgical margins, PORT did not improve OS, but OS was improved in those patients who underwent R1 resection combined with chemotherapy.Key pointsSignificant findings of the studySignificant findings of the study: Postoperative radiotherapy (PORT) has been recommended to treat patients with positive surgical margins. However, the existing evidence is controversial and high ‐level evidence is lacking.What this study addsWhat this study adds: The PORT group had markedly, but not statistically significant, longer median OS compared with the non ‐PORT group in patients with R1 resection. OS was significantly longer in the patients with R1 resection receiving adjuvant CRT than the surgery alone group.

Source: Thoracic Cancer - November 27, 2020 Category: Cancer & Oncology Authors: Meng Yuan, Yu Men, Jingjing Kang, Xin Sun, Maoyuan Zhao, Yongxing Bao, Xu Yang, Shuang Sun, Zeliang Ma, Jianyang Wang, Lei Deng, Wenqing Wang, Yirui Zhai, Wenyang Liu, Tao Zhang, Xin Wang, Nan Bi, Jima Lv, Jun Liang, Qinfu Feng, Dongfu Tags: ORIGINAL ARTICLE Source Type: research