Severe Fibrous Dysplasia in McCune-Albright Syndrome: A Need for Continuous Surveillance

Discussion: The post-mortem findings described aid understanding of the multiorgan involvement of MAS, providing new insights into possible pathogenetic mechanisms underlying the systemic effects ofGNAS mutations, and highlight a need for systematic surveillance for cerebrovascular changes in craniofacial FD that may be amenable to intervention to avoid catastrophic outcome.Horm Res Paediatr
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research