Microbiological findings in bile cultures of patients with acute cholangitis undergoing endoscopic retrograde cholangiography.

Microbiological findings in bile cultures of patients with acute cholangitis undergoing endoscopic retrograde cholangiography. Rev Esp Enferm Dig. 2020 Nov 24;: Authors: Robles Rivera FJ, Vilar Compte D, Manzano Robleda MDC Abstract Acute cholangitis (AC) is potentially fatal. Microbiological identification and susceptibility to antibiotics in every Hospital is essential to direct treatment. (1) In our hospital, a third-level cancer hospital, a retrospective, analytical study of 30 patients undergoing endoscopic retrograde cholangiography with AC and positive biliary culture (BC) was performed over a period of 6 months. We found that 90% of BC were monomicrobial, with E. coli in more than half of these patients (55%). It is worth mentioning that 27% of the strains were extended-spectrum beta-lactamase-producing Escherichia coli (ESBL). In the susceptibility analysis we found that 78% were sensitive to carbapenems, 66% to aminoglycids and 44% to piperacillin-tazobactam. Pseudomoas aeruginosa was found in 15% of the BC, but only 40% were sensitive to carbapenems. Despite the similarities of this cohort with other studies (1) (2) (3) (4) (5) it is worth mentioning that we found a high proportion of E.coli-ESBL and P.aeruginosa. Is important to mention that these patients had history of hospitalization (3 months), previous use of antibiotics, previous instrumentation of the bile duct, albumin <3.5g/dl and moderate AC (1). With the fin...
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research