Single electrode DBS through motor thalamus and caudal zona incerta for the treatment of tremor syndromes

Both nucleus ventralis lateralis (VL) and subthalamic nucleus (STN) DBS are effective in the treatment of essential tremor and Parkinson's disease tremor. Complex tremor syndromes may present the overlapping of different clinical aspects (at rest, postural and kinetic) and can be associated to syndromic forms (dystonic, cerebellar, spastic), but also to different etiologies (following brain injury or stroke). In these cases DBS does not always guarantees an effective outcome. A recent study proposed single electrode DBS of both ventralis oralis posterior (vop) thalamic nucleus and caudal Zona Incerta (cZI) for the treatment of complex tremor (Sitsapesan et al.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research