Optimizing Treatment Sequencing of Chemotherapy for Patients with Rectal Cancer: the KIR Randomized Phase II Trial

We conducted a phase 2 randomized, open-label, multicentre trial was in five institutions between 2010 and 2017(NCT01274962). Patients diagnosed with rectal cancer underwent baseline magnetic resonance imaging (MRI) of the pelvis, computed tomography scans of the chest, abdomen and pelvis, baseline serology including carcinogenic embryonic antigen testing. All patients underwent evaluation by a multidisciplinary tumor board including at least one colorectal surgeon, medical oncologist and radiation oncologist; a second radiologist reviewed imaging at tumor board for confirmation of eligibility.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research