Improvement of cerebral ischemia-reperfusion injury by L-3-n-butylphthalide through promoting angiogenesis.

In conclusion, our results demonstrated that L-NBP exerted significant beneficial effects on cerebral I/R injury in rats through promoting angiogenesis, which may be associated with the activation of Nrf2/HIF-1α/VEGF signaling pathway. Our results suggested that L-NBP could be a potential therapeutic drug for cerebral I/R injury. PMID: 33180154 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33180154?dopt=Abstract

Source: Experimental Brain Research - November 12, 2020 Category: Neuroscience Authors: Huang Y, Pan L, Wu T Tags: Exp Brain Res Source Type: research