Sensors, Vol. 20, Pages 6146: A Multi-Sensor Wearable System for the Quantitative Assessment of Parkinson ’s Disease

Sensors, Vol. 20, Pages 6146: A Multi-Sensor Wearable System for the Quantitative Assessment of Parkinson’s Disease Sensors doi: 10.3390/s20216146 Authors: Han Zhang Chuantao Li Wei Liu Jingying Wang Junhong Zhou Shouyan Wang The quantitative characterization of movement disorders and their related neurophysiological signals is important for the management of Parkinson’s disease (PD). The aim of this study is to develop a novel wearable system enabling the simultaneous measurement of both motion and other neurophysiological signals in PD patients. We designed a wearable system that consists of five motion sensors and three electrophysiology sensors to measure the motion signals of the body, electroencephalogram, electrocardiogram, and electromyography, respectively. The data captured by the sensors are transferred wirelessly in real time, and the outcomes are analyzed and uploaded to the cloud-based server automatically. We completed pilot studies to (1) test its validity by comparing outcomes to the commercialized systems, and (2) evaluate the deep brain stimulation (DBS) treatment effects in seven PD patients. Our results showed: (1) the motion and neurophysiological signals measured by this wearable system were strongly correlated with those measured by the commercialized systems (r > 0.94, p < 0.001); and (2) by completing the clinical supination and pronation frequency test, the frequency of motion as measured by th...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research