Bicuspid aortopathy - molecular involvement of microRNAs and MMP-TIMP.

CONCLUSION: Our findings indicate that aortic tissue microRNAs may reflect remodeling processes of the proximal aorta in BAV aortopathy. Specific aortic tissue microRNAs may exert their regulatory effects on the aortopathy through their impact on MMPs/TIMPs homeostasis at the level of greater curvature. PMID: 33090032 [PubMed - as supplied by publisher]
Source: Biomarkers - Category: Research Tags: Biomarkers Source Type: research