Anti-viral effect in chronic hepatitis B patients with normal or mildly elevated alanine aminotransferase.

CONCLUSION: Long term antiviral therapy inhibits HBV replication effectively in ALT<2×ULN CHB patients. PEG-IFN therapy is recommended for HBeAg+ patients with baseline HBsAg<4.37 log IU/ml and HBeAg- patients with baseline HBsAg<2.66 log IU/ml to achieve "low HBsAg at week 48".
PMID: 33065138 [PubMed - as supplied by publisher]

Source: Antiviral Research - October 13, 2020 Category: Virology Authors: Zhao Q, Liu K, Zhu X, Yan L, Ding Y, Xu Y, Lou S, Zhao G, Xie Q, Gao Y, Bao S, Wang H Tags: Antiviral Res Source Type: research