Role of densin ‐180 in mouse ventral hippocampal neurons in 24‐hr retention of contextual fear conditioning

ConclusionThis study shows that vHC densin ‐180 is necessary for stCFC memory formation and retrieval and suggests that both densin‐180 and p‐T305 CaMKIIα at 1 ~ 2 hr postshock are important for stCFC memory formation. We conclude that roles of hippocampal neuronal densin‐180 in CFC are temporally dynamic and differential dependi ng on the pattern of conditioning stimuli and its location along the dorsoventral axis of hippocampal formation.
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research