Wild Bitter Melon Exerts Anti-Inflammatory Effects by Upregulating Injury-Attenuated CISD2 Expression following Spinal Cord Injury.

Conclusion: To the best of our knowledge, this is the first study to report that CISD2 is an upstream modulator of the PPAR-β/NF-κB proinflammatory signaling pathway in neural cells, and that WBM can mitigate the injury-induced downregulation of CISD2 in SCI mice and LPS-stimulated ALT astrocytes. PMID: 33062068 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/33062068?dopt=Abstract

Source: Behavioural Neurology - October 20, 2020 Category: Neurology Authors: Kung WM, Lin CC, Kuo CY, Juin YC, Wu PC, Lin MS Tags: Behav Neurol Source Type: research