Wnt pathway modulation generates blastomere-derived mouse embryonic stem cells with different pluripotency features

ConclusionWnt and MAPK pathways have a key role in the successful derivation and pluripotency features of mESC from single precompaction blastomeres. Modulation of these pathways results in mESC lines with various degrees of na ïve-like and primed-like pluripotency features.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research