Advancement in research and therapy of NF1 mutant malignant tumors

The NF1 gene encodes neurofibromin, which is one of the primary negative regulatory factors of the Ras protein. Neurofibromin stimulates the GTPase activity of Ras to convert it from an active GTP-bound form to i...

Source: Cancer Cell International - October 9, 2020 Category: Cancer & Oncology Authors: Junyan Tao, Dantong Sun, Lina Dong, Hua Zhu and Helei Hou Tags: Review Source Type: research