Point-of-care multiplex-PCR enables germ identification in haemolytic uremic syndrome 94 h earlier than stool culture

AbstractHaemolytic uremic syndrome often affects children causing a relevant morbidity and mortality. We compared the time to diagnosis by multiplex-PCR and stool culture in 15 children from two centres. Multiplex-PCR accelerated the time to diagnosis by 94 (95% confidence interval, 80 –119;P = 0.0007) hours. Multiplex-PCR offers a time advantage of stool culture that may aid in earlier identification of outbreak clusters.

http://link.springer.com/10.1007/s10096-020-04060-x

Source: European Journal of Clinical Microbiology and Infectious Diseases - October 3, 2020 Category: Microbiology Source Type: research

More News: Children | Hemolytic Uremic Syndrome (HUS) | Infectious Diseases | Microbiology | Outbreaks