Long non ‑coding RNA PLK1S1 was associated with renal cell carcinoma progression by interacting with microRNA‑653 and altering C‑X‑C chemokine receptor 5 expression.

In conclusion, the present study revealed that PLK1S1 promoted tumor progression and sorafenib resistance in RCC through regulation of the miR‑653/CXCR5 axis, which may offer a novel treatment strategy for patients with RCC. PMID: 33000253 [PubMed - in process]
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research