Altered Mental Status and Hyponatremia After 20 Hours of Amiodarone Therapy.

Altered Mental Status and Hyponatremia After 20 Hours of Amiodarone Therapy. Tex Heart Inst J. 2020 Jun 01;47(3):229-232 Authors: Qi A, Moscona JC, Reed J, Le Jemtel TH Abstract A 66-year-old woman with no relevant medical history presented at the emergency department with new-onset atrial fibrillation. We initiated intravenous amiodarone therapy. At 20 hours, the patient experienced severe neurologic symptoms, hyponatremia, and syndrome of inappropriate antidiuretic hormone. We discontinued amiodarone, infused saline solution, and restricted the patient's fluid intake. She recovered in 3 days. This case illustrates that amiodarone-induced syndrome of inappropriate antidiuretic hormone with hyponatremia can occur far earlier than expected during acute amiodarone therapy. PMID: 32997783 [PubMed - in process]
Source: Texas Heart Institute Journal - Category: Cardiology Authors: Tags: Tex Heart Inst J Source Type: research