Intraoperative 68Ga-PSMA Cerenkov Luminescence Imaging for Surgical Margins in Radical Prostatectomy: A Feasibility Study

Conclusion: This feasibility showed that 68Ga-PSMA CLI is a new intraoperative imaging technique capable of imaging the entire specimen’s surface to detect PC tissue at the resection margin. Further optimization of the CLI protocol, or the use of lower-energy imaging tracers such as 18F-PSMA, is required to reduce false-positives. A larger study will be performed to assess diagnostic performance.

Source: Journal of Nuclear Medicine - September 30, 2020 Category: Nuclear Medicine Authors: Darr, C., Harke, N. N., Radtke, J. P., Yirga, L., Kesch, C., Grootendorst, M. R., Fendler, W. P., Costa, P. F., Rischpler, C., Praus, C., Haubold, J., Reis, H., Hager, T., Herrmann, K., Binse, I., Hadaschik, B. Tags: Clinical Source Type: research