Fshd / opmd / myotonic dystrophy

Gastro-intestinal disorders in myotonic dystrophy type 1 (DM1) are poorly understood and often overlooked by the medical community. The aim of this study is to describe gastro-intestinal manifestations of DM1 patients, to assess the impact on quality of life (GIQLI scale) and to identify factors associated. Thirty-two patients were included. Fifty percent reported digestive troubles. Abdominal pain and diarrhea were the most frequently reported ones (62% and 81% respectively). We did not find any factor linked to the presence of these disorders: (i) the duration of progression of the pathology, (ii) the level of CTG expansion, (iii) the degree of handicap or even (iv) the extra-neurological (cardiac and ophthalmological) involvement.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research