Identification of a novel gene expression signature associated with overall survival in patients with lung adenocarcinoma: A comprehensive analysis based on TCGA and GEO databases

Lung cancer is the second most common cancer and the leading cause of cancer death in both men and women [1]. Low lung cancer survival rates reflect the large proportion of patients diagnosed with metastatic disease, for which the 5-year relative survival rate is 5 %, far lower than a 57 % survival rate in patients with localized stage disease [1]. Non-small cell lung cancer (NSCLC) accounts for nearly 90 % of lung cancer cases, and lung adenocarcinoma (LUAD) represents the most common histologic subtype of NSCLC [2 –5].

Source: Lung Cancer - September 22, 2020 Category: Cancer & Oncology Authors: Jing Zhao, Chao Guo, Zhiming Ma, Hongsheng Liu, Chuhu Yang, Shanqing Li Source Type: research