Cancers, Vol. 12, Pages 2726: LncRNA Profiling Reveals That the Deregulation of H19, WT1-AS, TCL6, and LEF1-AS1 Is Associated with Higher-Risk Myelodysplastic Syndrome

Conclusions: we identified specific lncRNAs contributing to MDS pathogenesis and proposed cellular processes associated with these transcripts. Of the lncRNAs associated with patient prognosis, the level of H19 transcript might serve as a robust marker comparable to the clinical variables currently used for patient stratification.

Source: Cancers - September 22, 2020 Category: Cancer & Oncology Authors: Katarina Szikszai Zdenek Krejcik Jiri Klema Nikoleta Loudova Andrea Hrustincova Monika Belickova Monika Hruba Jitka Vesela Viktor Stranecky David Kundrat Pavla Pecherkova Jaroslav Cermak Anna Jonasova Michaela Dostalova Merkerova Tags: Article Source Type: research