CNIO identifies genetic factors associated to hand-foot syndrome in chemotherapy with capecitabine

(Centro Nacional de Investigaciones Oncol ó gicas (CNIO)) * The researchers studied more than 600,000 genetic variants in the genome of 166 patients treated with the chemotherapy drug capecitabine* Before undergoing treatment, the patients carrying the risk alleles for the hand-foot syndrome had low levels of two proteins that are key to the effective functioning of the skin barrier* The finding may help classify patients according to their genetic risk for developing this side effect of some cancer treatments
Source: EurekAlert! - Biology - Category: Biology Source Type: news