Osteonecrosis of the jaw associated with oral alendronate: case report

Medication-related osteonecrosis of the jaw (MRONJ) is clinically defined by persistent necrotic bone exposure for more than 8 weeks, history of antiresorptive or antiangiogenic agents, and no history of radiotherapy. A 67-year-old female, in treatment for hypercholesterolemia, insomnia, diabetes mellitus type 2, and hypertension, without adequate blood pressure and glycemic control. Reported treatment for osteoporosis with bisphosphonate (alendronate) for about 4 years, presents with bone exposure, for 6 months, in the anterior region of the maxilla, without symptoms.

Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - August 31, 2020 Category: ENT & OMF Authors: YURI KALININ, VANESSA CRISTINA DE BRANCO GON ÇALVES, SUELLEN VIEIRA DO NASCIMENTO, IVAN JOSé CORREIA NETO Tags: 20190698 Source Type: research