Hydrophilic magnetic molecularly imprinted nanobeads for efficient enrichment and high performance liquid chromatographic detection of 17beta-estradiol in environmental water samples.

Hydrophilic magnetic molecularly imprinted nanobeads for efficient enrichment and high performance liquid chromatographic detection of 17beta-estradiol in environmental water samples. Talanta. 2020 Dec 01;220:121367 Authors: Tian X, Song H, Wang Y, Tian X, Tang Y, Gao R, Zhang C Abstract Novel magnetic molecularly imprinted nanobeads for 17β-estradiol (E2), namely, E2-MMINs, were synthesized by molecularly imprinted polymers on the surface of magnetic nanobeads in aqueous solvents. The hydrophilic nanobeads were set up by adopting carboxyl group-functionalized Fe3O4 nanoparticles as carriers, E2 as template molecule, and dopamine as functional monomer. The synthesized E2-MMINs were investigated in different aspects including synthesis conditions, physical and chemical properties, and adsorption conditions. The experimental results show that the E2-MMINs present not only thin imprinting layers, stable crystal form, and fast magnetic separation ability, but also rapid kinetics (20 min), high binding amount (41.48 mg g-1), satisfactory specificity (imprinting factor = 8.07), and favorable reusability (adsorption efficiency > 94.8% after reusing for 10 times). Moreover, the method employing E2-MMINs combined with high performance liquid chromatography for the specific enrichment and determination of trace E2 has been developed with the low LOD (0.008 μg L-1), and the application in environmental water samples has been prove...
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research