“Concealed cardiomyopathy” as a cause of previously unexplained sudden cardiac arrest

Background: Genetic heart disease is a common cause of sudden cardiac arrest (SCA) in the young and those without an ischaemic precipitant. Identifying a cause of SCA in these patients allows for targeted care and family screening. Current guidelines recommend limited, phenotype-guided genetic testing in SCA survivors where a specific genetic condition is suspected and genetic testing is not recommended in clinically-idiopathic SCA survivors.Objective: To investigate the diagnostic utility of broad, multi-phenotype genetic testing in clinically-idiopathic SCA survivors.

Source: International Journal of Cardiology - September 11, 2020 Category: Cardiology Authors: Julia C. Isbister, Natalie Nowak BAnVetBioSc, Alexandra Butters, Laura Yeates, Belinda GrayMBBS, Raymond W. SyMBBS, Jodie InglesPhD, Richard D. BagnallPhD, Christopher SemsarianMBBS Source Type: research