PIWIL1 promotes gastric cancer via a piRNA-independent mechanism [Medical Sciences]

Targeted cancer therapy aims to achieve specific elimination of cancerous but not normal cells. Recently, PIWI proteins, a subfamily of the PAZ-PIWI domain (PPD) protein family, have emerged as promising candidates for targeted cancer therapy. PPD proteins are essential for small noncoding RNA pathways. The Argonaute subfamily partners with microRNA...

Source: Proceedings of the National Academy of Sciences - September 7, 2020 Category: Science Authors: Shuo Shi, Zhen-Zhen Yang, Sanhong Liu, Fan Yang, Haifan Lin Tags: Biological Sciences Source Type: research