A panorama of transcription-coupled repair in yeast chromatin [Genetics]

Cyclobutane pyrimidine dimers (CPDs) are predominant ultraviolet (UV) light-induced DNA lesions that can result in mutations and lead to skin cancers (1). CPD lesions are primarily repaired by nucleotide excision repair (NER), a highly conserved repair pathway (2). NER consists of two subpathways: transcription-coupled NER (TC-NER) and global genome NER...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Commentaries Source Type: research