TNF Inhibitor Pomalidomide Sensitizes Glioblastoma Cells to EGFR Inhibition.

CONCLUSIONS: We demonstrated that GBM resistance to EGFR inhibition was mediated by the activation of TNF. The combination of EGFR inhibitor and TNF inhibitor may have potential clinical implication in treating patients with EGFR-positive GBM.
PMID: 32826244 [PubMed - as supplied by publisher]

Source: Annals of Clinical and Laboratory Science - June 30, 2020 Category: Laboratory Medicine Authors: Luo Z, Wang B, Liu H, Shi L Tags: Ann Clin Lab Sci Source Type: research