Increase of urinary TIMP-2 and IGFBP7 as potential predictor of acute kidney injury requiring renal replacement therapy and patients' outcome following complex endovascular and open thoracic abdominal aortic aneurysm surgery.

Conclusions: TIMP2 × IGFBP7 level measured 6-12 hrs postoperatively may be useful as an early detectable biomarker for AKI requiring temporary renal replacement therapy. It seems not suited to predict patients' outcome following complex thoracoabdominal aortic surgery, regardless if performed by open or endovascular repair. PMID: 32815460 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32815460?dopt=Abstract

Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 19, 2020 Category: Surgery Authors: Gombert A, Kotelis D, Rückbeil MV, Barbati M, Martin L, Marx G, Grommes J, Jacobs MJ, Schälte G Tags: Vasa Source Type: research