Autophagic vacuole secretion triggered by chidamide participates in TRAIL apoptosis effect in breast cancer cells.
CONCLUSION: Our data are the first to demonstrate the synergistic effects of chidamide and TRAIL in BC cells, specifically, the pharmacological effects on cell death induction. These results lay a solid experimental and theoretical basis to solve the clinical resistance of chidamide.
PMID: 32787747 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Zhou W, Han H, Xu J, Sun T, Feng X Tags: Curr Pharm Des Source Type: research
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