May phytotherapy with polyphenols serve as a powerful approach for the prevention and therapy tool of novel coronavirus disease 2019 (covid-19)?

MAY PHYTOTHERAPY WITH POLYPHENOLS SERVE AS A POWERFUL APPROACH FOR THE PREVENTION AND THERAPY TOOL OF NOVEL CORONAVIRUS DISEASE 2019 (COVID-19)? Am J Physiol Endocrinol Metab. 2020 Aug 05;: Authors: Levy E, Delvin E, Marcil V, Spahis S Abstract Much more serious than the previous severe acute respiratory syndrome (SARS) coronavirus (CoV) outbreaks, the novel SARS-CoV-2 infection has spread speedily, affecting 213 countries and causing ~17,300,000 million cases and ~672,000 (~+1500/day) deaths globally (as of July 31th, 2020). The potentially fatal COVID-19, caused by air droplets and airborne as the main transmission modes, clearly induces a spectrum of respiratory clinical manifestations, but it also affects the immune, gastrointestinal, hematological, nervous and renal systems. The dramatic scale of disorders and complications arise from the inadequacy of current treatments, absence of a vaccine and specific anti-COVID-19 drugs to suppress viral replication, inflammation and additional pathogenic conditions. This highlights the importance of understanding the SARS-CoV-2 mechanisms of actions, and the urgent need of prospecting for new or alternative treatment options. The main objective of the present review is to discuss the challenging issue relative to the clinical utility of plants-derived polyphenols in fighting viral infections. Not only is the strong capacity of polyphenols highlighted in magnifying health benefits, but also...
Source: American Journal of Physiology. Endocrinology and Metabolism - Category: Physiology Authors: Tags: Am J Physiol Endocrinol Metab Source Type: research