MicroRNA miR-218-5p in Follicle Regeneration for Hair Regrowth

As a general rule, people care too much about their hair and too little about their blood vessels. One can live without hair. It is interesting to see both (a) just how much work goes into the regeneration of lost hair, and (b) just how little is known of the fine details by which the capacity to grow hair fades with age. It is this lack of knowledge that leads to the present state of uncertain and largely ineffective interventions for hair growth. No-one is entirely sure as to where the root of the problem lies, or where the most effective points of intervention might be. A great deal of exploration takes place, but success is all too much a matter of luck rather than design. With that in mind, the research materials here bridge a number of approaches to regeneration that are broadly used in the field: cell therapies, exosome therapies as a way of mimicking the effects of a cell therapy that primarily acts via cell signaling, and identification of specific signaling molecules that can change native cell behavior. Hair growth depends on the health of dermal papillae (DP) cells, which regulate the hair follicle growth cycle. Current treatments for hair loss can be costly and ineffective, ranging from invasive surgery to chemical treatments that don't produce the desired result. Recent hair loss research indicates that hair follicles don't disappear where balding occurs, they just shrink. If DP cells could be replenished at those sites, the thinking goes, then the foll...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs