Behavioral assessment of females with congenital adrenal hyperplasia.

CONCLUSION: Females with CAH had frequent and severe behavioral symptoms. Excess androgenization, which was in part due to suboptimal steroid therapy, was the cause of the behavioral problems. Therefore, early optimization of CAH management should be stressed to prevent psychological consequences. PMID: 32740726 [PubMed - as supplied by publisher]
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research

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Abstract The mechanical properties of anterior skull base (ASB) bones are not well understood due to their complex geometry and deep location. However, it is of particular interest for skull base surgeons to appraise the force range they can apply during procedures and know what kind of haptic feedback a simulation device should produce in order to be realistic for trainees. The aim of this study was to establish a measurement protocol to set the level of hydration state, temperature and curve analysis method for spherical depth sensing nanoindentation of ASB bones. A definitive screening design method was used to...
Source: Journal of the Mechanical Behavior of Biomedical Materials - Category: Materials Science Authors: Tags: J Mech Behav Biomed Mater Source Type: research
Publication date: Available online 15 September 2020Source: Progress in Materials ScienceAuthor(s): Santosh K. Gupta, Yuanbing Mao
Source: Progress in Materials Science - Category: Materials Science Source Type: research
Publication date: 22 September 2020Source: Cell Reports, Volume 32, Issue 12Author(s): Jinjing Yao, Bo Sun, Adam Institoris, Xiaoqin Zhan, Wenting Guo, Zhenpeng Song, Yajing Liu, Florian Hiess, Andrew K.J. Boyce, Mingke Ni, Ruiwu Wang, Henk ter Keurs, Thomas G. Back, Michael Fill, Roger J. Thompson, Ray W. Turner, Grant R. Gordon, S.R. Wayne Chen
Source: Cell Reports - Category: Cytology Source Type: research
Publication date: Available online 22 September 2020Source: NeuroscienceAuthor(s): Lisiane de Santana Souza, Priscila Albuquerque de Siqueira, Arlete Fernandes, Robertta Silva Martins, Regina Célia Cussa Kubrusly, Roberto Paes de Carvalho, Rodrigo A. Cunha, Alexandre dos Santos-Rodrigues, Pablo Pandolfo
Source: Neuroscience - Category: Neuroscience Source Type: research
Contributors : Hye-Yeon Seok ; Linh V Nguyen ; Yong-Hwan MoonSeries Type : Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaWe characterized and compared the biological and molecular functions of HRE1 α and HRE1β, two alternative splicing variants of HRE1, a AP2/ERF transcription factor in Arabidopsis. To compare the downstream regulatory mechanisms of HRE1α and HRE1β, Quant-Seq analysis was carried out. The experiment was designed to identify and compare differentially expressed genes (DEGs) between WT and HRE1α-overexpressing transgneic plants (OXs) and WT and H...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Arabidopsis thaliana Source Type: research
In this study, the impact of different metal salts in effective inactivation of enzyme activity was investigated by solid-phase microextraction (SPME) and GC/MS system in aqueous samples and kohlrabi matrix. A saturated solution of calcium chloride which is commonly used to stop enzyme activity in plant tissue inactivates the myrosinase–glucosinolate system. However, even without the participation of myrosinase, it changes the reaction pathway towards nitrile formation. The model experiment shows that optimum efficiency in inhibition of the enzyme system shows iron(III) ions, silver ions, and anhydride sodium sul...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Social interaction in individuals with Autism Spectrum Disorder (ASD) is characterized by qualitative impairments that highly impact quality of life. Bayesian theories in ASD frame an understanding of underlying mechanisms suggesting atypicalities in the evaluation of probabilistic links within the perceptual environment of the affected individual. To address these theories, the present study explores the applicability of an innovative Bayesian framework on social visual perception in ASD and demonstrates the use of gaze transitions between different parts of social scenes. We applied advanced analyses with Bayesian Hidden...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Gyroscope Therapeutics, a retinal gene therapy company, has developed the Orbit subretinal delivery system (SDS). The technology is designed to deliver therapies to the retina without the need for invasive procedures, such as vitrectomies, which invo...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Genetics Medicine Source Type: blogs
Abstract The present study explores the correlation between electroencephalographic and neuroimaging asymmetry index from EEG-MRI functional connectome and EEG power analysis in inattention, motion, and mixed profile subgroups of ADHD. Sixty-two subjects from Healthy Brain Network Biobank of the Child Mind Institute dataset were selected basing on the quotient score. From both MRI and EEG asymmetry index, Pearson's correlation, ANOVA, and partial least square analysis were performed matching left and right brain parcels and channels. The asymmetry index significantly correlated across subjects between fMRI and pow...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
The current operator of the facility is Rochester-based Peregrine Senior Living. Peregrine will continue managing the facility.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
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