Hypofractionated spinal stereotactic body radiation therapy for high-grade epidural disease.

CONCLUSIONS: In carefully selected patients, treatment of grade 2 ESCC disease with hypofractionated SBRT alone offers a 1-year cumulative incidence of LRF similar to that in low-grade ESCC and postseparation surgery adjuvant hypofractionated SBRT. Use of SBRT alone has a favorable safety profile and a low cumulative incidence of progressive disease requiring open surgical intervention (14.5%).
PMID: 32707555 [PubMed - as supplied by publisher]

Source: Journal of Neurosurgery.Spine - July 23, 2020 Category: Neurosurgery Authors: Rothrock RJ, Li Y, Lis E, Lobaugh S, Zhang Z, McCann P, Santos PMG, Yang TJ, Laufer I, Bilsky MH, Schmitt A, Yamada Y, Higginson DS Tags: J Neurosurg Spine Source Type: research