GSE154627 Distinct bacterial pathways influence the efficacy of antibiotics against Mycobacterium tuberculosis

Contributors : Michelle M Bellerose ; Megan K Proulx ; Clare M Smith ; Richard E Baker ; Thomas R Ioerger ; Christopher M SassettiSeries Type : OtherOrganism : Mycobacterium tuberculosis H37RvUnderstanding how M. tuberculosis survives during antibiotic treatment is necessary to rationally devise more effective tuberculosis chemotherapy regimens. Using genome-wide mutant fitness profiling and the mouse model of TB, we identified genes that alter antibiotic efficacy specifically in the infection environment.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Other Mycobacterium tuberculosis H37Rv Source Type: research