Combined use of tranexamic acid and rivaroxaban in posterior lumbar interbody fusion safely reduces blood loss and transfusion rates without increasing the risk of thrombosis —a prospective, stratified, randomized, controlled trial

ConclusionThe combined application of tranexamic acid and rivaroxaban significantly reduced the amount of blood loss and the transfusion rate during PLIF surgery and avoided an increase in the probability of thrombosis and the occurrence of epidural haematoma.Trial registration number and date of registrationChiCTR-18000164302018-06-01
Source: International Orthopaedics - Category: Orthopaedics Source Type: research