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Courtney ’s story: Piecing together a genetic puzzle
Courtney Whitmore was born 22 years ago with a cleft palate, two clubbed feet and fists that were so tightly clenched they couldn’t be pulled apart. Since Courtney was an otherwise happy and healthy baby, neither her parents nor her doctor saw cause to be concerned about these seemingly unrelated conditions. What they didn’t realize was that these were the first clues to a genetic puzzle that would take ten years to unravel. The next clue came at age 3. “One day my dad and I were playing peekaboo, and suddenly I couldn’t see,” says Courtney. “My parents rushed me to the hospital and the ...
Source: Thrive, Children's Hospital Boston - October 25, 2017 Category: Pediatrics Authors: Ellen Greenlaw Tags: Diseases & Conditions Our Patients’ Stories brain aneurysm Cardiovascular Genetics Program Cerebrovascular Surgery and Interventions Center Dr. Darren Orbach Dr. Lawrence Karlin Dr. Pedro del Nido Dr. Ronald Lacro Loeys-Dietz syndrome Source Type: news

ODI composite score improvements may not correlate with SF-12 PCS following fusion surgery for spondylolisthesis
A study published online in the journal Spine questions the appropriateness of composite Oswestry Disability Index (ODI) score in the evaluation of quality of life in studies of surgically treated degenerative spondylolisthesis patients.  (Source: Orthogate - Latest News)
Source: Orthogate - Latest News - October 22, 2017 Category: Orthopaedics Tags: Featured Editors Choice News Source Type: news

Medical News Today: Spondylolisthesis: Causes, symptoms, and treatments
In this article, learn about spondylolisthesis. What are the types and grades of spondylolisthesis, how is it diagnosed, and what are the causes? (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 14, 2017 Category: Consumer Health News Tags: Back Pain Source Type: news

7 medtech stories we missed this week: June 23, 2017
[Image from unsplash.com]From Guardant suing Foundation Medicine to Interson receiving 510(k) clearance for ultrasound probes, here are 7 medtech stories we missed this week but thought were still worth mentioning. 1. Guardant levels false advertising suit against Foundation Medicine Guardant Health announced in a June 22 press release that it has filed a lawsuit against Foundation Medicine for false advertising and unfair competition. Guardant Health is claiming that Foundation Medicine’s advertising causes harm to Guardant Health and its patients because it misleads oncologists about the sensitivity and accuracy of...
Source: Mass Device - June 23, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: 510(k) Business/Financial News Clinical Trials Food & Drug Administration (FDA) Implants Neurological Regulatory/Compliance Ultrasound EndoStim Foundation Medicine Inc. Guardant Health Interson Lee's Pharmaceutical Meditech Med Source Type: news

Can I Exercise with Spondylolisthesis and Stenosis?
Title: Can I Exercise with Spondylolisthesis and Stenosis?Category: Doctor's& Expert's views on SymptomsCreated: 6/21/2017 12:00:00 AMLast Editorial Review: 6/21/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - June 21, 2017 Category: Rheumatology Source Type: news

Your NEJM Group Today: Traumatic Spondylolisthesis of the Axis / Guiding New Moms Through the Healthcare System / Wisconsin Internist Opportunity (FREE)
By the Editors Here's what we chose for you from NEJM Group today:NEJM Clinical Practice Center: Images in clinical medicine: A 25-year-old man presented with neck … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 10, 2017 Category: Primary Care Source Type: news

A blast of mistakes: undiagnosed cervical spondylolisthesis following a bomb explosion - Caruso R, Marrocco L, Piccione E, Wierzbicki V.
We report a case of spondylolisthesis following a bomb explosion, which went undiagnosed for a long time ... (Source: SafetyLit)
Source: SafetyLit - April 1, 2017 Category: Global & Universal Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

Current Concepts in the Management of Spondylolisthesis Current Concepts in the Management of Spondylolisthesis
The diagnosis and management of spondylolisthesis can be complex and challenging. Find out what there is to currently know about this deformity.Current Orthopaedic Practice (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - February 27, 2017 Category: Surgery Tags: Orthopaedics Journal Article Source Type: news

Minimally Invasive vs Open Surgery for Spondylolisthesis Minimally Invasive vs Open Surgery for Spondylolisthesis
How do these two approaches for the surgical treatment of spondylolisthesis compare in terms of outcomes?Spine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 22, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

How Common are Herniated Disks in Children?
Discussion Intervertebral disk herniation occurs at the same locations in pediatric patients as adults with L4-L5 and L5-S1 being the most common. Patients often (30-60% for lumbar disk patients) have a direct trauma or sports related injury that is identified before the onset of pain. There is also a group of morbidly obese patients who probably have degenerative disease. In adults and children, lumbar disk herniation is also seen with repetitive or excessive axial loading, poor conditioning, decreased range of motion and history of prior back injury. Disk herniation is caused by vertebral motion that causes increased int...
Source: PediatricEducation.org - September 19, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Conditions with Confusing Names
Spondylolysis, Spondylolisthesis, Spondylitis & Spondylosis These four conditions affect the lumbar spine and may be confusing. What is the difference between spondylolysis, spondylolisthesis, spondylitis, and spondylosis? Spondylolysis (pars interarticularis Defect) - Used to describe the anatomic defect or break of the pars interarticularis of the vertebral arch. Spondylolysis usually occurs in the lower lumbar spine, especially the L5 vertebrae. It usually appears as a radiolucent gap on lateral X-ray. It occurs in about 5% of the population; it is not present at birth but develops over time and may run in fam...
Source: Healthy Living - The Huffington Post - August 18, 2016 Category: Consumer Health News Source Type: news

Spondylolisthesis
Title: SpondylolisthesisCategory: Diseases and ConditionsCreated: 6/30/2009 12:00:00 AMLast Editorial Review: 7/20/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - July 20, 2016 Category: Rheumatology Source Type: news

Study: Insurance restrictions on lumbar fusions push procedure volumes down
An insurance policy limit on lumbar fusion procedures helped slash costs and medically unnecessary surgeries in North Carolina, and the approach could work nationally, according to new research published in the journal Spine. “The commercial insurance policy change had its intended effect of reducing fusion operations for indications with less evidence of effectiveness, without changing rates for other indications or resulting in an overall reduction in spine surgery,” the authors wrote. “Broader adoption of the policy could significantly reduce the national rates of fusion operations and associated costs...
Source: Mass Device - June 9, 2016 Category: Medical Equipment Authors: Mark Hollmer Tags: Spinal Surgical Wall Street Beat Source Type: news

Fusion Adds Little to Laminectomy for Lumbar Stenosis Fusion Adds Little to Laminectomy for Lumbar Stenosis
Adding spinal fusion to decompression laminectomy did not improve outcomes for patients with lumbar spinal stenosis, even if they also had degenerative spondylolisthesis. Medscape Medical News (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - April 14, 2016 Category: Orthopaedics Tags: Orthopaedics News Source Type: news

Medtech approvals: FDA releases December 2015 PMAs
The Food & Drug Administration today released a list of pre-market approvals granted in December 2015: Summary of PMA Originals & Supplements Approved Originals: 2 Supplements: 81 Summary of PMA Originals Under Review Total Under Review: 58 Total Active: 32 Total On Hold: 26 Summary of PMA Supplements Under Review Total Under Review: 599 Total Active: 423 Total On Hold: 176 Summary of All PMA Submissions Originals: 3 Supplements: 92 Summary of PMA Supplement PMA Approval/Denial Decision Times Number of Approvals: 81 Number of Denials: 0 Average Days Fr Receipt to Decision (Total Time): 163.1 FDA Time: 140....
Source: Mass Device - February 2, 2016 Category: Medical Equipment Authors: MassDevice Tags: Food & Drug Administration (FDA) Regulatory/Compliance Source Type: news

Surgical Treatment of Lumbar Degenerative SpondylolisthesisSurgical Treatment of Lumbar Degenerative Spondylolisthesis
What is the preferred operative approach for degenerative spondylolisthesis, and which factors may influence the treatment choice? A survey of spine surgeons provides some insight. Spine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 16, 2015 Category: Consumer Health News Tags: Orthopaedics Journal Article Source Type: news

Yoga Can Naturally Heal Crippling Injuries Without Surgery
When you feel her calming energy, you would never guess Kata went through a crippling car accident that left her in constant pain. At the time, the damage to her neck and spine was so severe, her doctors started preparing her for multiple surgeries. They told her she’d be in a neck brace for the rest of her life. But today, Kata is living pain free. Her spine is long and relaxed, and she has full range of motion in her neck. And she did it without surgery. Instead of going under the knife, Kata turned to yoga. What is yoga? Yoga is a mind-body practice that combines stretching exercises, controlled breathing and ...
Source: Al Sears, MD Natural Remedies - October 16, 2015 Category: Complementary Medicine Authors: Al Sears Tags: Fitness Anti-Aging disease prevention natural cures telomeres wellness yoga Source Type: news

Medtech approvals: FDA releases June 2015 PMAs
The FDA today released its list of the pre-market approvals it granted for medical devices in June 2015: Summary of PMA Originals & Supplements Approved Originals: 5 Supplements: 80 Summary of PMA Originals Under Review Total Under Review: 53 Total Active: 22 Total On Hold: 31 Summary of PMA Supplements Under Review Total Under Review: 575 Total Active: 418 Total On Hold: 157 Summary of All PMA Submissions Originals: 4 Supplements: 72 Summary of PMA Supplement PMA Approval/Denial Decision Times Number of Approvals: 80 Number of Denials: 0 Average Days Fr Receipt to Decision (Total Time): 115.2 FDA Time: 9...
Source: Mass Device - August 20, 2015 Category: Medical Equipment Authors: MassDevice Tags: Food & Drug Administration (FDA) Regulatory/Compliance Source Type: news

Medtech approvals: FDA releases May 2015 PMAs
The FDA today released its list of the pre-market approvals it granted for medical devices in May 2015: Summary of PMA Originals & Supplements Approved Originals: 5 Supplements: 51 Summary of PMA Originals Under Review Total Under Review: 55 Total Active: 26 Total On Hold: 29 Summary of PMA Supplements Under Review Total Under Review: 547 Total Active: 379 Total On Hold: 168 Summary of All PMA Submissions Originals: 1 Supplements: 62 Summary of PMA Supplement PMA Approval/Denial Decision Times Number of Approvals: 51 Number of Denials: 0 Average Days Fr Receipt to Decision (Total Time): 109.5 FDA Time: 86...
Source: Mass Device - August 6, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Regulatory/Compliance Source Type: news

UPDATE: NuVasive beats The Street, closes DoJ probe
UPDATED July 30, 2015, with details on Justice Dept. probe. NuVasive Inc. (NSDQ:NUVA) posted 2nd-quarter earnings that topped expectations on Wall Street and closed out its $14 million settlement with the U.S. Justice Dept. San Diego-based NuVasive reported profits of $10.3 million, or 20¢ per share, on sales of $202.9 million for the 3 months ended June 30, marking a swing to profits from losses of -$4.1 million and 6.4% sales growth, compared with Q2 2014. Adjusted to exclude 1-time items, earnings per share were 31¢, a full 6¢ ahead of expectations on The Street. “We are pleased to re...
Source: Mass Device - July 30, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Legal News MassDevice Earnings Roundup Regulatory/Compliance Nuvasive Source Type: news

Spinal surgery diminishes low back pain, improves sexual function
Chronic low back pain can limit everyday activities, including sex. 70 percent of patients consider sexual activity "relevant" to their life quality, and patients who receive surgical treatment for spinal spondylolisthesis (DS) and spinal stenosis (SS) -- common degenerative conditions most often occurring in older adults -- were twice as likely to report no pain during sex. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 24, 2015 Category: Science Source Type: news

How Do You Diagnose Hypermobility?
Discussion Hypermobility can be seen in several different clinical entities. These include generalized joint hypermobility, joint hypermobility syndrome, Marfan syndrome, Ehlers-Danlos syndrome and Osteogenesis Imperfecta. For adults, a Beighton score of at least 4 or 5 is used as a definition of hypermobility. For children a score of 5 or 6 is used as a definition. (see scoring system below). Generalized joint hypermobility is hypermobility with few or no symptoms. If they occur, knee symptoms are the most common. Joint hypermobility syndrome has hypermobility along with other symptoms such as pain, reduced muscle stren...
Source: PediatricEducation.org - February 23, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Spinal Surgery for Patients Over 80
A new study appearing in the February 4th issue of the Journal of Bone & Joint Surgery (JBJS) found significant benefit from surgical treatment for lumbar spinal stenosis with and without degenerative spondylolisthesis - debilitating spinal conditions causing leg and back pain, numbness and weakness - and no higher overall complication rate and no higher mortality for patients age 80 and older when compared to patients younger than age 80. (Source: Disabled World)
Source: Disabled World - February 9, 2015 Category: Disability Tags: Surgery and Operations Source Type: news

Promising results from minimally invasive back surgery
Beaumont research findings published in the February online issue of Spine shows that patients who have a low back surgery called minimally invasive transforaminal lumbar interbody fusion, end up better off in many ways than patients who have more invasive surgery to alleviate debilitating pain."About 90 percent of adults experience low back pain in their lifetime, which can be caused by spinal instability, stenosis, spondylolisthesis, and symptomatic degenerative disc disease," says Mick Perez-Cruet, M.D. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 6, 2014 Category: Consumer Health News Tags: Back Pain Source Type: news

Single vs Multilevel Fusion for Spondylolisthesis, StenosisSingle vs Multilevel Fusion for Spondylolisthesis, Stenosis
Which is the best surgical option for single-level degenerative spondylolisthesis with multilevel lumbar stenosis? The SPORT study reports. Spine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 3, 2013 Category: Consumer Health News Tags: Orthopaedics Journal Article Source Type: news

If Degenerative Cervical Spine Disease Doesn't Progress, Is Surgery Necessary?
Follow-up data on patients with degenerative disease of the upper (cervical) spinal vertebrae show little or no evidence of worsening degeneration over time, according to a study in the journal Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. For many patients with "unstable" cervical degenerative spondylolisthesis, observation may be a better choice than surgery, according to the new research by Dr Moon Soo Park and colleagues of Medical College of Hallym University, Republic of Korea... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 21, 2013 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news