Outcome and patterns of radiation associated brain image changes after proton therapy for head and neck skull base cancers

Radiation therapy for head neck cancers (HNCs) at the skull base can result in high doses of radiation delivered to the brain, potentially leading to radiation-associated image changes (RAIC) (1). Often the diagnosis of RAIC is based solely on radiographic findings on post-treatment MRIs obtained for routine cancer surveillance purposes. For HNCs, information on RAIC stems largely from studies in patients with nasopharyngeal cancers (NPC) treated with Intensity Modulated Radiation Therapy (IMRT), with reported incidences of temporal lobe RAIC ranging between 2% and 14% (2 –12).

Source: Radiotherapy and Oncology - July 13, 2020 Category: Radiology Authors: Grete May Engeseth, Sonja Stieb, Abdallah Sherif Radwan Mohamed, Renjie He, Camilla Hanquist Stokkev åg, Marianne Brydøy, Clifton Dave Fuller, Adam S Garden, David I Rosenthal, Jack Phan, William H Morrison, Jay P Reddy, Richard Wu, Xiaodong Zhang, Stev Tags: Original Article Source Type: research