Licoricidin improves neurological dysfunction after traumatic brain injury in mice via regulating FoxO3/Wnt/ β-catenin pathway

In conclusion, Licoricidin exerted neuroprotective effect on TBI model and the effect was possibly due to its antioxidative effect and antiapoptotic effect via regulating the FoxO3/Wnt/β-catenin pathway. Licoricidin may be a candidate drug for TBI therapy.

http://link.springer.com/10.1007/s11418-020-01434-5

Source: Journal of Natural Medicines - July 11, 2020 Category: Drugs & Pharmacology Source Type: research