Musashi-1 promotes stress-induced tumor progression through recruitment of AGO2

Conclusion: Our findings highlight novel molecular functions of MSI1 during stress-induced carcinomatous recurrence, and suggest a new therapeutic strategy for refractory malignancies by targeting MSI1 translocation and its interaction with AGOs.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Hsiao-Yun Chen, Mong-Lien Wang, Benoit Laurent, Chih-Hung Hsu, Ming-Teh Chen, Liang-Ting Lin, Jia Shen, Wei-Chao Chang, Jennifer Hsu, Mien-Chie Hung, Yi-Wei Chen, Pin-I Huang, Yi-Ping Yang, Chung-Pin Li, Hsin-I Ma, Chung-Hsuan Chen, Wen-Chang Lin, Shih-Hw Tags: Research Paper Source Type: research