The efficacy of Bifidobacterium quadruple viable tablet in the treatment of diarrhea predominant irritable bowel syndrome: protocol for a randomized, double-blind, placebo-controlled, multicenter trial

DiscussionThis multicenter randomized controlled trial may provide high-quality evidence on the efficacy of theBifidobacterium quadruple viable tablet for IBS-D on both physical and mental dimensions in China. To fill the gap of previous probiotic intervention studies, in addition, this study will also present safety assessment which will be a significant emphasis.Trial registrationChiCTR1800017721. Registered on 10 August 2018.
Source: Trials - Category: Research Source Type: clinical trials