Risk of bias in studies investigating novel diagnostic biomarkers for Heart Failure with Preserved Ejection Fraction. A systematic review

ConclusionThe majority of current diagnostic HFpEF biomarker studies have a high risk of bias, reducing the reproducibility and the potential for clinical care. Methodological well ‐designed studies with a uniform reference diagnosis are urgently needed to determine the incremental value of circulating biomarkers for the diagnosis of HFpEF.

Source: European Journal of Heart Failure - June 26, 2020 Category: Cardiology Authors: M.T.H.M. Henkens, S. Remmelzwaal, E.L. Robinson, A.J. van Ballegooijen, M.A. Barandiar án Aizpurua, J.A.J. Verdonschot, A.G. Raafs, J. Weerts, M.R. Hazebroek, S. van Sanders‐Wijk, M.L. Handoko, H.M. Ruijter, C.S.P. Lam, R.A. Boer, W.J. Pa Tags: Research Article Source Type: research