A CGRP receptor antagonist peptide formulated for nasal administration to treat migraine
Conclusions(34Pro,35Phe)CGRP27 –37 is a potent CGRP receptor antagonist bothin vitro andin vivo, and it can be formulated as a dry powder with no loss of activity indicating its potential as a nasally formulated anti ‐migraine medicine.
Source: Journal of Pharmacy and Pharmacology - Category: Drugs & Pharmacology Authors: Bengt Mentzer,
Andrew F. Russo,
Zhang Zhongming,
Adisa Kuburas,
Patrick M. Killoran,
Vera D ’Aloisio,
Laura Nizic,
Vicky Capel,
David A. Kendall,
Christopher R. Coxon,
Gillian A. Hutcheon Tags: Research Paper Source Type: research