GR silencing impedes the progression of castration-resistant prostate cancer through the JAG1/NOTCH2 pathway via up-regulation of microRNA-143-3p.

CONCLUSION: The key findings of the current study demonstrated that silencing GR suppressed the progression of CRPC through the JAG1/NOTCH2 pathway via up-regulation of miR-143-3p. PMID: 32568179 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32568179?dopt=Abstract

Source: Cancer Biomarkers - June 24, 2020 Category: Cancer & Oncology Tags: Cancer Biomark Source Type: research